MODAFIN BENEFITS AND EFFECTS

Substance
Modafinil

Package
200mg (30 pills)

WHAT IS MODAFIN?

MODAFIN BENEFITS AND EFFECTS,Modafin (Modafinil) is a medication that promotes wakefulness. It is thought to work by altering the natural chemicals (neurotransmitters) in the brain.

Modafin is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder.

Modafin may also be used for purposes not listed in this medication guide.

MODAFIN INDICATIONS

Modafin decreases extreme sleepiness due to narcolepsy and other sleep disorders such as difficult/irregular breathing during sleep (e.g., obstructive sleep apnea/hypopnea syndrome-OSAHS).

It is also used to help you stay awake during work hours for people with work schedules that interfere with a normal sleep routine (shift work sleep disorder-SWSD).

It is not known how Modafin works to increase wakefulness. It is thought to work by affecting certain chemicals in the brain that control the sleep/wake cycle.

Modafin does not make up for lack of sleep and should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder.

This medication is not recommended for use in children

MODAFIN BENEFITS AND EFFECTS

HOW SHOULD I USE MODAFIN?

Use Modafin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Modafin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Modafin refilled.
• Modafin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Modafin refilled.
• Take Modafin by mouth with or without food.
• Take Modafin in the morning unless otherwise directed by your doctor.
• If you miss a dose of Modafin, take it as soon as possible. If you do not remember until late afternoon or evening, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Modafin.

USES OF MODAFIN IN DETAILS

Modafin is used to treat excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea (problems in breathing while asleep) and chronic shift work.

More: https://www.ndrugs.com/?s=modafin

MODAFIN DESCRIPTION

Modafin is a stimulant drug marketed as a ‘wakefulness promoting agent’ and is one of the stimulants used in the treatment of narcolepsy.

Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by Modafin.

The prexin neuron activation is associated with psychoactivation and euphoria.

The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine.

Modafin activates glutamatergic circuits while inhibiting GABA.

MODAFIN DOSAGE

Dosage In Narcolepsy And Obstructive Sleep Apnea (OSA)

The recommended dosage of Modafin for patients with narcolepsy or OSA is 200 mg taken orally once a day as a single dose in the morning.

Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose.

Dosage In Shift Work Disorder (SWD)

The recommended dosage of Modafin for patients with SWD is 200 mg taken orally once a day as a single dose approximately 1 hour prior to the start of their work shift.

Dosage Modifications In Patients With Severe Hepatic Impairment

In patients with severe hepatic impairment, the dosage of Modafin should be reduced to one-half of that recommended for patients with normal hepatic function.

Use In Geriatric Patients

Consideration should be given to the use of lower doses and close monitoring in geriatric patients.

How supplied

Dosage Forms And Strengths

• 100 mg – capsule-shaped, white to off white, tablet, debossed with “Modafin” on one side and “100 MG” on the other.
• 200 mg – capsule-shaped, white to off white, scored, tablet, debossed with “Modafin” on one side and “200 MG” on the other.

Storage And Handling

Modafin® (Modafin) tablets are available as follows:

100 mg: Each capsule-shaped, white to off white tablet is debossed with “Modafin” on one side and “100 MG” on the other. NDC 63459-101-30 – Bottles of 30

200 mg: Each capsule-shaped, white to off white, scored tablet is debossed with “Modafin” on one side and “200 MG” on the other. NDC 63459-201-30 – Bottles of 30

Storage

Store at 20°-25°C (68°-77°F).